Invention Grant
- Patent Title: Compounds and methods for treating cancer
-
Application No.: US15577845Application Date: 2016-06-03
-
Publication No.: US10464897B2Publication Date: 2019-11-05
- Inventor: James Bradner , Michael Erb , Jun Qi
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Cooley LLP
- Agent Heidi A. Erlacher; Chen Chen
- International Application: PCT/US2016/035641 WO 20160603
- International Announcement: WO2016/196879 WO 20161208
- Main IPC: C07D211/44
- IPC: C07D211/44 ; C07D401/14 ; C07D401/04 ; C07D413/04 ; C07D239/78 ; C07D471/04 ; C07D211/58 ; C07D213/30 ; A61P35/00
Abstract:
The present application relates to compounds comprising an ester, a thioester, or a hydrazide moiety and methods of synthesizing these compounds. The present application also relates to pharmaceutical compositions containing the compounds and methods of treating cell proliferative disorders mediated by the Hh signaling pathway, such as cancer, by administering the compounds and pharmaceutical compositions to subjects in need thereof.
Public/Granted literature
- US20180148410A1 COMPOUNDS AND METHODS FOR TREATING CANCER Public/Granted day:2018-05-31
Information query
