Invention Grant
- Patent Title: Substituted tetrahydropyrans as CCR2 modulators
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Application No.: US15692811Application Date: 2017-08-31
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Publication No.: US10464934B2Publication Date: 2019-11-05
- Inventor: Junfa Fan , Jaroslaw Kalisiak , Rebecca M. Lui , Venkat Reddy Mali , Jeffrey P. McMahon , Jay P. Powers , Hiroko Tanaka , Yibin Zeng , Penglie Zhang
- Applicant: CHEMOCENTRYX, INC.
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo PC
- Main IPC: C07D309/04
- IPC: C07D309/04 ; C07D471/04 ; A61K31/4545 ; C07D405/04 ; A61K31/453 ; A61K31/496 ; C07D413/14 ; A61K31/536 ; C07D405/14 ; A61K31/4725 ; A61P35/00 ; A61P37/00 ; A61K45/06

Abstract:
Compounds are provided that are modulators of the CCR2 receptor. The compounds have the general formula (I): and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of CCR2 receptors.
Public/Granted literature
- US20180086756A1 SUBSTITUTED TETRAHYDROPYRANS AS CCR2 MODULATORS Public/Granted day:2018-03-29
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