Invention Grant
- Patent Title: Multilayered nanoparticle and methods of manufacturing and using the same
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Application No.: US15104123Application Date: 2014-12-09
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Publication No.: US10465189B2Publication Date: 2019-11-05
- Inventor: Subramanian Venkatraman , Tzee Ling Tina Wong , Bjorn Neu
- Applicant: NANYANG TECHNOLOGICAL UNIVERSITY , SINGAPORE HEALTH SERVICES PTE LTD
- Applicant Address: SG Singapore SG Singapore
- Assignee: NANYANG TECHNOLOGICAL UNIVERSITY,SINGAPORE HEALTH SERVICES PTE LTD
- Current Assignee: NANYANG TECHNOLOGICAL UNIVERSITY,SINGAPORE HEALTH SERVICES PTE LTD
- Current Assignee Address: SG Singapore SG Singapore
- Agency: Seed IP Law Group LLP
- International Application: PCT/SG2014/000587 WO 20141209
- International Announcement: WO2015/088445 WO 20150618
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/713 ; A61K48/00 ; C12N15/11 ; A61K9/50 ; A61K9/51
Abstract:
The invention relates to a multilayered nanoparticle for delivery of RNA to a cell and methods of manufacturing and using the same. The multilayered nanoparticle has a core nanoparticle coated by alternating positively and negatively charged polymer layers, wherein the at least one of the negatively charged polymer layers is RNA.
Public/Granted literature
- US20160319280A1 MULTILAYERED NANOPARTICLE AND METHODS OF MANUFACTURING AND USING THE SAME Public/Granted day:2016-11-03
Information query
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