Invention Grant
- Patent Title: Quantitative [Fe]-MRI (femri) of anti-PSMA-conjugated SPIONs based on PSMA expression levels
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Application No.: US15574431Application Date: 2016-05-13
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Publication No.: US10466326B2Publication Date: 2019-11-05
- Inventor: Laurel Sillerud
- Applicant: STC.UNM
- Applicant Address: US NM Albuquerque
- Assignee: STC. UNM
- Current Assignee: STC. UNM
- Current Assignee Address: US NM Albuquerque
- Agency: Keith Vogt, Ltd.
- Agent Keith A. Vogt
- International Application: PCT/US2016/032489 WO 20160513
- International Announcement: WO2016/187052 WO 20161124
- Main IPC: G01R33/56
- IPC: G01R33/56 ; G01R33/465 ; B82Y15/00 ; G06T7/00
![Quantitative [Fe]-MRI (femri) of anti-PSMA-conjugated SPIONs based on PSMA expression levels](/abs-image/US/2019/11/05/US10466326B2/abs.jpg.150x150.jpg)
Abstract:
A method of measuring the concentration of a magnetic material in an object using magnetic resonance imaging comprising administering magnetic material to the object; obtaining a set of T1-weighted and T2-weighted images of the object in order to determine a background magnetic resonance imaging signal intensity and measurements of the background nuclear magnetic relaxation times (T1, T2) of the object without magnetic material; and obtaining a set of T1-weighted and T2-weighted magnetic resonance images of the object with magnetic materials added; measuring effect of magnetic material on the relaxation times; and converting the T1-weighted and T2-weighted images into a set of contrast images which are subtracted from each other to yield a contrast difference image proportional to the concentration of the magnetic material.
Public/Granted literature
- US20180143278A1 Quantitative [Fe]-MRI (Femri) of anti-PSMA-Conjugated SPIONs Based on PSMA Expression Levels Public/Granted day:2018-05-24
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