A rehabilitation system includes a portable patient workstation configured to facilitate in-home rehabilitation therapy. In some embodiments, the workstation includes a computer configured to host computer-based activities that provide rehabilitative exercise to a patient when the patient participates in the activities, a monitor electrically connected to the computer and configured to display screens of the computer-based activities, a table upon which the monitor can be supported, a tabletop console supported on the table, the console including multiple integral user interface devices that are connected to the computer and adapted to receive patient inputs while the patient is participating in the activities, and a network interface device with which data can be transmitted and received by the patient workstation via a network.