A micro LED display panel and a manufacturing method thereof are provided. The micro LED display panel includes: a substrate, a plurality of micro LEDs disposed on the substrate and arranged in an array, a transparent encapsulation layer covering the plurality of micro LEDs, and a quantum dot (QD) layer disposed on the encapsulation layer. By adding the QD layer on the encapsulation layer, the short wavelength light emitted by the micro LEDs excites the QD layer to emit light, so that the micro LEDs and the QD layer form the basic display units of the micro LED display panel to expand the gamut of micro LED display panel and improve display quality of the micro LED display panel.