A wireless device receives at least one radio resource control message comprising one or more configuration parameters of a cell. A control order for transmission of a random access preamble is received via the cell. A transmission power is determined for the random access preamble based on a pathloss measurement. When the one or more configuration parameters comprise one or more parameters of a channel state information reference signal (CSI-RS) for the cell: the pathloss measurement is based on the CSI-RS; and the determining the transmission power employs a power offset value indicated by the one or more configuration parameters. When the one or more configuration parameters do not comprise CSI-RS parameters for the cell: the pathloss measurement is based on at least one synchronization signal; and the determining the transmission power does not employ the power offset value. The random access preamble is transmitted based on the transmission power.