A fabric-based pressure sensor assembly utilizing in ionic material and conductive material is disclosed. The sensing device can be applied in several various wearable health and biomedical applications on complex body topologies. As an alternative to conventional flexible sensors, the fabric-based sensor assembly yields high device sensitivity and desirable parameters for pressure sensing in a wearable construct. The sensor assembly enables rapid mechanical responses (in the milliseconds range) for high-frequency biomechanical signals, e.g., blood pressure pulses and body movements. The fabrication process for the device is low-cost highly compatible with existing industrial manufacturing processes.