The present disclosure provides a defect repairing method of a flexible display panel including: providing a transparent substrate, the transparent substrate including a first surface and a second surface opposite to each other; forming a flexible substrate on the first surface; forming an array substrate layer on the surface of the flexible substrate, wherein the array substrate layer includes a display area and a peripheral area; irradiating the display area with a patterned laser on the second surface; and annealing the transparent substrate on which the array substrate layer and the flexible substrate are formed. The defect repairing method of the flexible display panel can quickly and easily repair various defects caused by the laser irradiation of the flexible display panel so as to optimize the display effect of the flexible display panel and improve the yield of the flexible display panel.