A method includes obtaining a switch zone set configuration for a switch fabric, the switch zone set configuration comprising one or more switch zones each comprising one or more of host devices interconnected with one or more storage systems via one or more Fibre Channel (FC) switches. The method also includes provisioning the switch zone set configuration in the FC switches and enabling FC ports of the FC switches and establishing the one or more switch zones of the switch zone set configuration in the storage systems. The method further includes validating connectivity by determining whether specified FC ports of the FC switches are connected to specified host bus adapter (HBA) ports of the host devices and the storage systems in accordance with the provisioned switch zone set configuration, and activating the one or more switch zones in an infrastructure environment responsive to successful validation of the connectivity.