Invention Grant
- Patent Title: Oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth and application thereof
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Application No.: US15538283Application Date: 2015-06-25
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Publication No.: US10525077B2Publication Date: 2020-01-07
- Inventor: Xuegen Wang , Qing Ye , Yijun Sun
- Applicant: Nanjing New Industry Investment Group Co., Ltd , Jiangsu Keygen Biotech Corp., Ltd
- Applicant Address: CN Nanjing, Jiangsu CN Nanjing, Jiangsu
- Assignee: JIANGSU KEYGEN BIOTECH CORP., LTD,NANJING NEW INDUSTRY INVESTMENT GROUP CO., LTD
- Current Assignee: JIANGSU KEYGEN BIOTECH CORP., LTD,NANJING NEW INDUSTRY INVESTMENT GROUP CO., LTD
- Current Assignee Address: CN Nanjing, Jiangsu CN Nanjing, Jiangsu
- Agency: Rankin, Hill & Clark LLP
- Priority: CN201410844012 20141230
- International Application: PCT/CN2015/082403 WO 20150625
- International Announcement: WO2016/107117 WO 20160707
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K31/7125 ; A61K31/713 ; C12N15/113 ; A61P35/00
Abstract:
The present invention provides an oligodeoxy nucleotide for preparing drugs for inhibiting tumor growth and an application thereof. The core sequence of the oligodeoxy nucleotide is TTYSGGAAWT, wherein Y is C or T; S is C or G; and W is A or T. The oligodeoxy nucleotide above further comprises an antisense strand and a modified type thereof. The oligodeoxy nucleotide according to the present invention plays a role of inhibiting the tumor growth in vitro and vivo, and is expected to be used for preparing drugs for inhibiting tumor growth, with high specificity and high inhibition ratio.
Public/Granted literature
- US20180142238A1 OLIGODEOXY NUCLEOTIDE FOR PREPARING DRUGS FOR INHIBITING TUMOR GROWTH AND APPLICATION THEREOF Public/Granted day:2018-05-24
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