Invention Grant
- Patent Title: ATF5 peptide variants and uses thereof
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Application No.: US16239217Application Date: 2019-01-03
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Publication No.: US10525100B2Publication Date: 2020-01-07
- Inventor: Barry Jay Kappel , Gene Merutka , Jimmy Andrew Rotolo
- Applicant: Sapience Therapeutics, Inc.
- Applicant Address: US NY Harrison
- Assignee: Sapience Therapeutics, Inc.
- Current Assignee: Sapience Therapeutics, Inc.
- Current Assignee Address: US NY Harrison
- Agency: Grimes & Yvon LLP
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/47 ; A61P35/00 ; C12N15/85
Abstract:
Provided are activating transcription factor 5 (ATF5) peptides having a truncated ATF5 leucine zipper region and, optionally, a cell-penetrating region, compositions comprising the ATF5 peptides, and methods of inhibiting proliferation of and promoting cytotoxicity in a neoplastic cell using the ATF5 peptides.
Public/Granted literature
- US20190201483A1 ATF5 Peptide Variants and Uses Thereof Public/Granted day:2019-07-04
Information query
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