Invention Grant
- Patent Title: Mutant huntingtin-mediated protein dysfunction
-
Application No.: US15295538Application Date: 2016-10-17
-
Publication No.: US10525108B2Publication Date: 2020-01-07
- Inventor: Robert Friedlander , Hiroko Yano
- Applicant: University Of Pittsburgh—Of The Commonwealth System Of Higher Education , WASHINGTON UNIVERSiTY
- Applicant Address: US PA Pittsburgh US MO St. Louis
- Assignee: University of Pittsburgh—Of The Commonwealth System Of Higher Education,WASHINGTON UNIVERSITY
- Current Assignee: University of Pittsburgh—Of The Commonwealth System Of Higher Education,WASHINGTON UNIVERSITY
- Current Assignee Address: US PA Pittsburgh US MO St. Louis
- Agency: Baker Botts L.L.P.
- Main IPC: A61K38/45
- IPC: A61K38/45 ; A61K38/17 ; C12N15/62 ; C12N9/12
Abstract:
The present invention relates to methods of inhibiting neurodegeneration in a subject suffering from or genetically at risk and/or destined to develop Huntington's Disease comprising increasing, in neurons of the subject, the activity of the TIM23 mitochondrial protein import complex.
Public/Granted literature
- US20170028034A1 MUTANT HUNTINGTIN-MEDIATED PROTEIN DYSFUNCTION Public/Granted day:2017-02-02
Information query
IPC分类:
