Invention Grant
- Patent Title: Methods for inducing an immune response against human immunodeficiency virus infection in subjects undergoing antiretroviral treatment
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Application No.: US16385062Application Date: 2019-04-16
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Publication No.: US10525123B2Publication Date: 2020-01-07
- Inventor: Frank Tomaka , Maria Grazia Pau , Johanna Schuitemaker , Dan Barouch , Jintanat Ananworanich , Merlin Robb , Nelson L. Michael , Jerome Kim
- Applicant: Janssen Vaccines & Prevention B.V. , Beth Israel Deaconess Medical Center, Inc. , Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. , THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY
- Applicant Address: NL Leiden US MA Boston US MD Bethesda US MD Fort Detrick
- Assignee: Janssen Vaccines & Prevention B.V.,Beth Israel Deaconess Medical Center, Inc.,THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.,The Government of The United States, as represented by The Secretary Of The Army
- Current Assignee: Janssen Vaccines & Prevention B.V.,Beth Israel Deaconess Medical Center, Inc.,THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.,The Government of The United States, as represented by The Secretary Of The Army
- Current Assignee Address: NL Leiden US MA Boston US MD Bethesda US MD Fort Detrick
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; C12N7/00 ; A61K39/21 ; A61K31/711 ; A61P31/18

Abstract:
Methods for inducing an immune response against Human Immunodeficiency Virus (HIV) in HIV-infected subjects undergoing antiretroviral therapy (ART) are described. The methods include administering an adenovirus vector primer vaccine and a modified vaccinia virus (MVA) vector booster vaccine encoding mosaic HIV antigens.
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