Invention Grant
- Patent Title: Modified lipopolysaccharide glycoform and method of use
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Application No.: US15586781Application Date: 2017-05-04
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Publication No.: US10525126B2Publication Date: 2020-01-07
- Inventor: Thomas J. Silhavy , Marcin Grabowicz , Daniel Kahne , Matthew Lebar , Dorothee Andres
- Applicant: The Trustees of Princeton University
- Applicant Address: US NJ Princeton US MA Cambridge
- Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee: THE TRUSTEES OF PRINCETON UNIVERSITY,PRESIDENT AND FELLOWS OF HARVARD COLLEGE
- Current Assignee Address: US NJ Princeton US MA Cambridge
- Agency: Meagher Emanuel Laks Goldberg & Liao, LLP
- Main IPC: A61K39/39
- IPC: A61K39/39 ; C12N9/00 ; C07H13/06 ; C12P21/00 ; C07H15/04 ; C07K4/00 ; C12N15/04 ; A61K39/00
Abstract:
The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described.
Public/Granted literature
- US20170239350A1 MODIFIED LIPOPOLYSACCHARIDE GLYCOFORM AND METHOD OF USE Public/Granted day:2017-08-24
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