Invention Grant
- Patent Title: Conjugate of polyethylene glycol and anesthetic, and preparation method thereof
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Application No.: US15848987Application Date: 2017-12-20
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Publication No.: US10525143B2Publication Date: 2020-01-07
- Inventor: Jinliang Wang , Zewang Feng , Hui Zhu , Meina Lin , Yan Liu , Xuan Zhao
- Applicant: JenKem Technology Co., Ltd. (Tianjin)
- Applicant Address: CN Tianjin
- Assignee: JENKEM TECHNOLOGY CO., LTD. (TIANJIN)
- Current Assignee: JENKEM TECHNOLOGY CO., LTD. (TIANJIN)
- Current Assignee Address: CN Tianjin
- Agency: Flener IP & Business Law
- Agent Zareefa B. Flener
- Priority: CN201510354709 20150624
- Main IPC: A61K47/60
- IPC: A61K47/60 ; A61K9/06 ; A61K9/08 ; A61K9/20 ; A61K9/70 ; A61K47/10 ; A61K47/18 ; A61K9/14 ; A61K9/48
Abstract:
A conjugate represented by general formula (I), wherein R0 is a C1-6 alkyl, B is an anesthetic, and A is a linking group, and a quaternary ammonium salt is formed at the linking position between B and R0. The conjugate has a prolonged analgesic effect, and can be used in postoperative analgesia or treatment for chronic pain.
Public/Granted literature
- US20180110867A1 CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF Public/Granted day:2018-04-26
Information query
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