Invention Grant
- Patent Title: Dream neuronal calcium sensor-modulating compounds, and therapeutic uses thereof
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Application No.: US15538341Application Date: 2015-12-17
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Publication No.: US10526276B2Publication Date: 2020-01-07
- Inventor: Marta Gutiérrez Rodríguez , Pilar Cercos Pita , María Rosario Herranz Herranz , María Teresa García López , María Carmen Valenzuela Miranda , José Ramón Naranjo Orovio , Britt Mellstrom , Paz González Pérez , María Mercedes Martín Martínez , José Manuel Dopazo Santos
- Applicant: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS , CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES NEURODEGENERATIVAS (CIBERNED) , UNIVERSIDAD AUTÓNOMA DE MADRID
- Applicant Address: ES Madrid ES Madrid ES Madrid
- Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS,CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES NEURODEGENERATIVAS (CIBERNED),UNIVERSIDAD AUTÓNOMA DE MADRID
- Current Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS,CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES NEURODEGENERATIVAS (CIBERNED),UNIVERSIDAD AUTÓNOMA DE MADRID
- Current Assignee Address: ES Madrid ES Madrid ES Madrid
- Agency: Womble Bond Dickinson (US) LLP
- Priority: ES201431898 20141222
- International Application: PCT/ES2015/070923 WO 20151217
- International Announcement: WO2016/102727 WO 20160630
- Main IPC: C07C233/33
- IPC: C07C233/33 ; C07D233/64 ; C07C233/31 ; C07C233/55 ; C07C235/38 ; C07C237/42
Abstract:
The present invention relates to a group of compounds with a structural nucleus derived from phenylacetamide, having the following formula (I): that can modulate the DREAM neuronal calcium sensor. Consequently, the present invention also relates to the use of these compounds for the treatment or prevention of disorders or diseases in which DREAM levels are above or below physiologically normal levels.
Public/Granted literature
- US20180037538A1 DREAM NEURONAL CALCIUM SENSOR-MODULATING COMPOUNDS, AND THERAPEUTIC USES THEREOF Public/Granted day:2018-02-08
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