Invention Grant
- Patent Title: (2-amino-4-(arylamino)phenyl carbamates
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Application No.: US15526668Application Date: 2015-11-13
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Publication No.: US10526280B2Publication Date: 2020-01-07
- Inventor: Peter Wipf , Athanassios Tzounopoulos
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2015/060627 WO 20151113
- International Announcement: WO2016/077724 WO 20160519
- Main IPC: C07C271/28
- IPC: C07C271/28 ; C07D305/06 ; C07D333/20 ; C07D277/28 ; A61P25/28 ; A61P27/16 ; A61P1/00 ; A61P25/00 ; C07B59/00 ; C07C323/33

Abstract:
A compound, or pharmaceutically acceptable salt thereof, having a formula I of: wherein R1 is H or optionally-substituted alkyl; R2 is optionally-substituted alkyl; R3 and R4 are each independently H or optionally-substituted alkyl; R5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R6 and R7 are each independently H, deuterium, optionally-substituted alkyl, or R6 and R7 together form a carbocyclic; R8 is optionally-substituted thiazolyl, optionally-substituted thiophenyl, or substituted phenyl, provided that if R8 is 4-halophenyl, then R2 is substituted alkyl or branched alkyl or at least one of R6 or R7 is not H; and R30, R31 and R32 are each independently H, deuterium, halogen, substituted sulfanyl, or optionally-substituted alkoxy.
Public/Granted literature
- US20180127357A1 (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES Public/Granted day:2018-05-10
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