Invention Grant
- Patent Title: LSD1 inhibitors and uses thereof
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Application No.: US15567978Application Date: 2016-04-22
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Publication No.: US10526287B2Publication Date: 2020-01-07
- Inventor: Brian K. Albrecht , James Edmund Audia , Alexandre Côté , Martin Duplessis , Victor S. Gehling , Jean-Christophe Harmange , Rishi G. Vaswani
- Applicant: Constellation Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Constellation Pharmaceuticals, Inc.
- Current Assignee: Constellation Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Michael J. DeGrazia
- International Application: PCT/US2016/028864 WO 20160422
- International Announcement: WO2016/172496 WO 20161027
- Main IPC: C07D211/22
- IPC: C07D211/22 ; C07D211/26 ; C07D309/20 ; C07D215/44 ; C07D317/28 ; C07D401/04 ; C07D401/06 ; C07D403/04 ; C07D403/06 ; C07D403/10 ; C07D405/04 ; C07D239/30 ; C07C215/44 ; C07D417/06 ; C07D263/32 ; C07D205/12 ; C07D207/32 ; C07D211/36 ; C07D213/64 ; C07D305/06 ; C07C255/58 ; C07C211/09 ; C07C211/36 ; C07C211/40 ; C07C215/14 ; C07C217/08 ; C07C229/10 ; C07C229/38 ; C07C229/46 ; C07C233/41 ; C07C237/06 ; C07C255/24 ; C07C215/42 ; C07C255/30 ; C07D211/58 ; C07D211/76 ; C07D213/38 ; C07D213/69 ; C07D213/73 ; C07D295/195 ; A61P35/00

Abstract:
Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with LSD1. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with LSD1.
Public/Granted literature
- US20180290976A1 LSD1 INHIBITORS AND USES THEREOF Public/Granted day:2018-10-11
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