Invention Grant
- Patent Title: Pentapeptide associated with integrin receptor alpha vbeta3
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Application No.: US15568315Application Date: 2015-10-26
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Publication No.: US10526370B2Publication Date: 2020-01-07
- Inventor: Yueqing Gu , Congying Zhang , Menglu Zhao , Qian Wang , Caiping Tian , Yuxi Liu
- Applicant: CHINA PHARMACEUTICAL UNIVERSITY
- Applicant Address: CN Nanjing, Jiangsu
- Assignee: CHINA PHARMACEUTICAL UNIVERSITY
- Current Assignee: CHINA PHARMACEUTICAL UNIVERSITY
- Current Assignee Address: CN Nanjing, Jiangsu
- Agency: Oliff PLC
- Priority: CN201510190462 20150420
- International Application: PCT/CN2015/092827 WO 20151026
- International Announcement: WO2016/169239 WO 20161027
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K5/00 ; C07K7/06 ; A61P35/00 ; G01N33/574
Abstract:
A pentapeptide associated with integrin receptor αvβ3, which has a sequence of arginine-tryptophan-arginine-asparagine-methionine. The pentapeptide targets tumor cells highly expressing αvβ3, but not tumor cells lowly expressing αvβ3 and normal cells. Accordingly, the pentapeptide is useful in the diagnosis and treatment of cancers.
Public/Granted literature
- US20180141974A1 PENTAPEPTIDE ASSOCIATED WITH INTEGRIN RECEPTOR ALPHA VBETA3 Public/Granted day:2018-05-24
Information query
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