Invention Grant
- Patent Title: RNA polymerase variants
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Application No.: US16432541Application Date: 2019-06-05
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Publication No.: US10526629B2Publication Date: 2020-01-07
- Inventor: Amy E. Rabideau , Athanasios Dousis , Kanchana Ravichandran , Elissa Hobert
- Applicant: ModernaTX, Inc.
- Applicant Address: US MA Cambridge
- Assignee: ModernaTX, Inc.
- Current Assignee: ModernaTX, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12P19/34
Abstract:
The present disclosure provides, in some aspects, variant RNA polymerases, the use of which increases transcription efficiency while reducing the number of double-stranded RNA contaminates and run-on transcripts produced during an in vitro transcription reaction.
Public/Granted literature
- US20190309337A1 RNA POLYMERASE VARIANTS Public/Granted day:2019-10-10
Information query
