Provided are a computer program product, system, and method for monitoring correctable errors on a bus interface to determine whether to redirect traffic to another bus interface. A processing unit sends Input/Output (I/O) requests from a host to a storage over a first bus interface to a first device adaptor, wherein the first device adaptor provides a first connection to the storage. A determination is made as to whether a number of correctable errors on the first bus interface exceeds an error threshold. The correctable errors are detected and corrected in the first bus interface by hardware of the first bus interface. In response to determining that the number of correctable errors on the first bus interface exceeds the error threshold, at least a portion of I/O requests are redirected to use a second bus interface to connect to a second device adaptor providing a second connection to the storage.