Methods, systems, and computer-readable storage medium including a computer program product for defending against cyber-attacks are provided. One method includes receiving, by a processor, program code and automatically generating a chronomorphic binary for the program code. The method further includes storing the chronomorphic binary in an executable memory space and diversifying the executable memory space for the chronomorphic binary during runtime of the program code. A system includes memory configured for storing a defense module and a processor connected to the memory. The processor, when executing the defense module, is configured for performing the above-referenced method. One computer program product includes computer code for performing the above-referenced method.