Invention Grant
- Patent Title: Thermo-responsive gelling artificial lacrima
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Application No.: US16110056Application Date: 2018-08-23
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Publication No.: US10532026B2Publication Date: 2020-01-14
- Inventor: Takeshi Yamamura , Ayaka Yamamuro , Emi Izukura , Moto Kimura , Tomohiro Otsuka
- Applicant: WAKAMOTO PHARMACEUTICAL CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: WAKAMOTO PHARMACEUTICAL CO., LTD.
- Current Assignee: WAKAMOTO PHARMACEUTICAL CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Nath, Goldberg & Meyer
- Agent Joshua B. Goldberg
- Priority: JP2017-086512 20170425; JP2017-249891 20171226
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61P27/02 ; A61K47/32 ; A61K47/10 ; A61K47/38 ; A61K9/06 ; A61P27/04 ; A61K31/194 ; A61K47/12 ; A61K31/5383

Abstract:
The present invention is an aqueous solution which contains two types of methyl celluloses, polyethylene glycol, polyvinylpyrrolidone, and citric acid or a pharmaceutically acceptable salt thereof. The composition of the present invention maintains a low viscosity around room temperature, but the composition is suddenly increased in the viscosity due to heat around the body temperature and has thixotropy even after gelation.
Public/Granted literature
- US20180360746A1 THERMO-RESPONSIVE GELLING ARTIFICIAL LACRIMA Public/Granted day:2018-12-20
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