Invention Grant
- Patent Title: Mineralized foot-and-mouth disease virus like particles, and preparation method and use thereof
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Application No.: US16027289Application Date: 2018-07-04
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Publication No.: US10532092B2Publication Date: 2020-01-14
- Inventor: Huichen Guo , Shiqi Sun , Ping Du , Zhidong Teng , Ruikang Tang , Ruibo Zhao , Jiaxi Ru , Yanquan Wei , Yun Zhang , Yuan Gao , Junwu Ma , Xiangtao Liu , Hong Yin
- Applicant: Lanzhou Veterinary Research Institute Chinese Academy of Agricultural Sciences , Zhejiang University
- Applicant Address: CN Lanzhou CN Hangzhou
- Assignee: LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES,ZHEJIANG UNIVERSITY
- Current Assignee: LANZHOU VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES,ZHEJIANG UNIVERSITY
- Current Assignee Address: CN Lanzhou CN Hangzhou
- Agency: Matthias Scholl P.C.
- Agent Matthias Scholl
- Priority: CN201710539048 20170704
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K39/00
Abstract:
Foot-and-mouth disease virus like particles, the particles including a structural protein VP0, a structural protein VP1 including a mineralization peptide, a structural protein VP3, and a calcium phosphate coat. The structural protein VP1 including a mineralization peptide is encoded by a gene sequence represented by SEQ ID NO. 7, SEQ ID NO. 8 or SEQ ID NO. 9. The structural protein VP0 is encoded by a gene sequence represented by SEQ ID NO. 2. The structural protein VP3 is encoded by a gene sequence represented by SEQ ID NO. 3. The calcium phosphate coat covers the structural protein VP0, the structural protein VP1 including a mineralization peptide, and the structural protein VP3.
Public/Granted literature
- US20190008944A1 MINERALIZED FOOT-AND-MOUTH DISEASE VIRUS LIKE PARTICLES, AND PREPARATION METHOD AND USE THEREOF Public/Granted day:2019-01-10
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