Invention Grant
- Patent Title: Modified virus-like particles of CMV
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Application No.: US15520676Application Date: 2015-10-20
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Publication No.: US10532107B2Publication Date: 2020-01-14
- Inventor: Martin Bachmann , Andris Zeltins , Paul Pumpens
- Applicant: SAIBA GMBH
- Applicant Address: CH Rämismühle
- Assignee: SAIBA GMBH
- Current Assignee: SAIBA GMBH
- Current Assignee Address: CH Rämismühle
- Agency: Medler Ferro Woodhouse & Mills PLLC
- Priority: EP14189897 20141022
- International Application: PCT/EP2015/074269 WO 20151020
- International Announcement: WO2016/062720 WO 20160428
- Main IPC: C12N7/00
- IPC: C12N7/00 ; A61K47/64 ; A61K39/12 ; A61K39/35 ; C07K14/005 ; A61K39/00 ; A61K39/015 ; A61K39/145 ; A61K39/155 ; A61K39/39 ; C07K14/33 ; C07K14/725 ; A61K39/08

Abstract:
The present invention relates to virus-like particles of plant virus Cucumber Mosaic Virus (CMV), and in particular to modified VLPs of CMV comprising Th cell epitopes, in particular universal Th cell epitopes. Furthermore, these modified VLPs serve as, preferably, vaccine platform, for generating immune responses, in particular antibody responses, against antigens linked to said modified VLPs. The presence of the Th cell epitopes, in particular universal Th cell epitopes, led to a further increase in the generated immune response.
Public/Granted literature
- US20170312371A1 MODIFIED VIRUS-LIKE PARTICLES OF CMV Public/Granted day:2017-11-02
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