A refill bottle, such as a laundry refill bottle, is disclosed that can be used with a consumer refill station to reuse the bottle over and over. The refill bottle includes automatic flow control valves, that allow the bottle to be filled, handled, dispensed from, and refilled innumerable times without a cap. The elimination of a cap alleviates the manufacturer and consumer of the tasks of installing, loosening, tightening, removing, and reinstalling or replacing the cap. The refillable bottle uses flow control valves, specifically an automatic filling valve, an automatic pressure vent valve, a manual/automatic dispensing valve, and an automatic vacuum vent valve. The refill bottle enables liquid and air to be exchanged during filling, handling, dispensing, and refilling.