Invention Grant
- Patent Title: Quinolone-3-diarylethers
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Application No.: US15215103Application Date: 2016-07-20
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Publication No.: US10532983B2Publication Date: 2020-01-14
- Inventor: Michael Riscoe , Aaron Nilsen , Galen Miley , Rolf Winter , Sovitj Pou , Jane Xu Kelly , Rozalia Dodean
- Applicant: OREGON HEALTH & SCIENCE UNIVERSITY , THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS
- Applicant Address: US OR Portland
- Assignee: Oregon Health & Science University
- Current Assignee: Oregon Health & Science University
- Current Assignee Address: US OR Portland
- Main IPC: C07D215/22
- IPC: C07D215/22 ; C07D405/12 ; C07D409/12 ; A61P33/00
Abstract:
Disclosed are derivative compounds of ELQ-300 that include an ester at position 4. These compounds have enhanced properties relative to ELQ-300. Also disclosed are pharmaceutical compositions comprising the compounds and methods of treating and preventing malaria infections involving administering the pharmaceutical compositions to the subject.
Public/Granted literature
- US20170022164A1 QUINOLONE-3-DIARYLETHERS Public/Granted day:2017-01-26
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