Invention Grant
- Patent Title: Methods for modulating Ataxin 2 expression
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Application No.: US15973088Application Date: 2018-05-07
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Publication No.: US10533178B2Publication Date: 2020-01-14
- Inventor: C. Frank Bennett , Susan M. Freier , Stefan M. Pulst , Daniel R. Scoles , Gene Hung
- Applicant: Ionis Pharmaceuticals, Inc. , University of Utah Research Foundation
- Applicant Address: US CA Carlsbad US UT Salt Lake City
- Assignee: Ionis Pharmaceuticals, Inc.,University of Utah Research Foundation
- Current Assignee: Ionis Pharmaceuticals, Inc.,University of Utah Research Foundation
- Current Assignee Address: US CA Carlsbad US UT Salt Lake City
- Agency: Ballard Spahr LLP
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K48/00 ; C12N5/00
Abstract:
Disclosed herein are methods for decreasing Ataxin 2 mRNA and protein expression. Such methods are useful to treat, prevent, or ameliorate Ataxin 2 associated diseases, disorders, and conditions. Such Ataxin 2 associated diseases include spinocerebellar ataxia type 2 (SCA2), amyotrophic lateral sclerosis (ALS), and parkinsonism.
Public/Granted literature
- US20190017047A1 METHODS FOR MODULATING ATAXIN 2 EXPRESSION Public/Granted day:2019-01-17
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