Invention Grant
- Patent Title: Method for screening for sunlight protection functional material and method for evaluating sunlight protection effect
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Application No.: US15559348Application Date: 2015-03-19
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Publication No.: US10533992B2Publication Date: 2020-01-14
- Inventor: Hyoung June Kim , Min Sik Choi , Ji Yong Jung , Ju Yearl Park , Tae Ryong Lee , Dong Wook Shin , Eui Dong Son , Min Jung Chae
- Applicant: AMOREPACIFIC CORPORATION
- Applicant Address: KR Seoul
- Assignee: AMOREPACIFIC CORPORATION
- Current Assignee: AMOREPACIFIC CORPORATION
- Current Assignee Address: KR Seoul
- Agency: Merchant & Gould P.C.
- International Application: PCT/KR2015/002659 WO 20150319
- International Announcement: WO2016/148324 WO 20160922
- Main IPC: G01N33/52
- IPC: G01N33/52 ; G01N33/53 ; G01N33/68 ; G01N33/50 ; A61K8/27 ; A61K8/29 ; A61K33/30 ; A61K33/00 ; A61K33/24 ; A61K8/37 ; A61K8/49 ; A61Q17/04

Abstract:
Unlike a conventional method for evaluating a degree of ultraviolet protection through visual evaluation, the disclosed method for measuring a sunlight protection function can accurately and objectively measure and determine a degree of sunlight protection by measuring a change due to a material to be measured with respect to an expression amount of skin tissue antimicrobial peptides (AMPs) in skin cells, which decrease from exposure to sunlight, and/or a generation amount of S-nitrosylated protein. Additionally, the disclosed measurement method can determine whether blue/violet light of wavelengths of 400-500 nm, which induces the most skin damage among visible rays, is blocked and provide a more specified sunlight protection effect evaluation result. Moreover, by using the disclosed measurement method, a degree of sunlight protection can be indexed, and a sunlight protection composition for protecting normal skin from the blue/violet light can be provided.
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