A system and method for single authentication to a multi-tenancy single-page application hosted in a plurality of different datacenters. The method comprises: receiving, from a client device, a login request to access the single-page application; receiving an access token in response to an authentication of a user of the client device, wherein the access token designates at least tenant identification data; determining a datacenter of the plurality of different datacenters executing an instance of the single-page application supporting a tenant of the authenticated user; retrieving, from the determined datacenter, a single web page of the single-page application, wherein the retrieved signal web page includes at least references to resources pointing to a location of the determined datacenter; and serving the web single page to the client device.