Invention Grant
- Patent Title: Pharmaceutical compositions and their use for treatment of cancer and autoimmune diseases
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Application No.: US16123167Application Date: 2018-09-06
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Publication No.: US10537587B2Publication Date: 2020-01-21
- Inventor: Wei He
- Applicant: ZHEJIANG DTRM BIOPHARMA CO. LTD.
- Applicant Address: CN Hangzhou
- Assignee: ZHEJIANG DTRM BIOPHARMA CO. LTD.
- Current Assignee: ZHEJIANG DTRM BIOPHARMA CO. LTD.
- Current Assignee Address: CN Hangzhou
- Agency: Steptoe & Johnson LLP
- Agent Z. Ying Li
- Priority: CN201510119944 20150319
- Main IPC: A61K31/635
- IPC: A61K31/635 ; A61K31/519 ; A61K31/436 ; A61K31/454 ; A61K31/4162 ; A61K45/06 ; C07D487/04 ; A61P35/00 ; A61K31/52

Abstract:
Described herein are combination therapies for cancer (such as lymphoid malignancies) and immune diseases (such as autoimmune diseases and inflammatory diseases). The therapies comprise the combined use of inhibitors of BTK, mTOR kinase, and Bcl-2 or their signaling pathways, and immunomodulatory drugs. Also described are pharmaceutical compositions and kits comprising these inhibitors.
Public/Granted literature
- US20180360853A1 Pharmaceutical Compositions and Their Use for Treatment of Cancer and Autoimmune Diseases Public/Granted day:2018-12-20
Information query