Invention Grant
- Patent Title: Antibodies to TIGIT
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Application No.: US15449665Application Date: 2017-03-03
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Publication No.: US10537633B2Publication Date: 2020-01-21
- Inventor: J. Yun Tso , Naoya Tsurushita , Omar Duramad
- Applicant: JN Biosciences LLC , Abmuno Therapeutics LLC
- Applicant Address: US CA Mountain View US CA Berkeley
- Assignee: JN Biosciences LLC,Abmuno Therapeutics LLC
- Current Assignee: JN Biosciences LLC,Abmuno Therapeutics LLC
- Current Assignee Address: US CA Mountain View US CA Berkeley
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K16/46 ; A61K39/395 ; C07K16/30 ; A61K39/00
Abstract:
The invention provides monoclonal antibodies that specifically bind to TIGIT. The monoclonal antibodies have the capacity for substantial activation of T cells and natural killer cells by inhibiting binding of TIGIT to CD155. The monoclonal antibodies can be used for treatment of cancer and infectious disease, among other applications.
Public/Granted literature
- US20170281764A1 ANTIBODIES TO TIGIT Public/Granted day:2017-10-05
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