Invention Grant
- Patent Title: Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
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Application No.: US15472186Application Date: 2017-03-28
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Publication No.: US10537658B2Publication Date: 2020-01-21
- Inventor: Rajendra Kasinath , Craig Ernsberger , Stephanie Vass , Steven N. Ginn , Haibo Qu , Weidong Tong
- Applicant: DePuy Synthes Products, Inc.
- Applicant Address: US MA Raynham
- Assignee: DePuy Synthes Products, Inc.
- Current Assignee: DePuy Synthes Products, Inc.
- Current Assignee Address: US MA Raynham
- Agency: Barnes & Thornburg LLP
- Main IPC: A61L27/04
- IPC: A61L27/04 ; A61L27/12 ; A61L27/06 ; A61L27/32 ; A61L31/08 ; A61L27/56 ; A61L27/50 ; A61L27/58 ; A61L27/02

Abstract:
An orthopedic implant having a metal surface and a hydroxyapatite layer comprising gallium ions therein disposed on at least part of the metal surface is described. The hydroxyapatite layer has an average crystallite size of less than about 75 nm in at least one direction and dissolves for more than 2 hours in vitro. The hydroxyapatite layer is substantially free of carbonate. The coating, which is formed on a sodium titanate surface, has increased shear strength and tensile strength. The coating is formed by a solution deposited hydroxyapatite process under inert conditions. The pH of the solution varies by less than 0.1 pH unit/hour during coating formation.
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