Invention Grant
- Patent Title: Adamantane and memantine derivatives as peripheral NMDA receptor antagonists
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Application No.: US15747507Application Date: 2016-07-26
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Publication No.: US10538482B2Publication Date: 2020-01-21
- Inventor: Marc Humbert , Sylvia Cohen-Kaminsky , Sébastien Dumas , Gilles Bru-Mercier , Mouad Alami , Jean-Daniel Brion , Samir Messaoudi , Gilles Galvani
- Applicant: Institut National de la Santé et de la Recherche Médicale (INSERM) , Assistance Publique-Hôpitaux De Paris , Centre National de la Recherche Scientifique (CNRS) , Université Paris-Sud
- Applicant Address: FR Paris FR Paris FR Paris FR Orsay
- Assignee: Institut National de la Santé et de la Recherche Médicale (INSERM),Assistance Publique-Hopitaux de Paris,Centre National de la Recherche Scientifique (CNRS),Université Paris-Sud
- Current Assignee: Institut National de la Santé et de la Recherche Médicale (INSERM),Assistance Publique-Hopitaux de Paris,Centre National de la Recherche Scientifique (CNRS),Université Paris-Sud
- Current Assignee Address: FR Paris FR Paris FR Paris FR Orsay
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: EP15306228 20150728
- International Application: PCT/EP2016/067846 WO 20160726
- International Announcement: WO2017/017116 WO 20170202
- Main IPC: C07C211/62
- IPC: C07C211/62 ; C07C215/08 ; C07C251/38 ; C07C211/63 ; A61P9/12
Abstract:
The present invention relates to cationic compounds of formula (I) for use as peripheral NMDA receptor antagonists.
Public/Granted literature
- US20180215699A1 NOVEL ADAMANTANE AND MEMANTINE DERIVATIVES AS PERIPHERAL NMDA RECEPTOR ANTAGONISTS Public/Granted day:2018-08-02
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