Invention Grant
- Patent Title: Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof
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Application No.: US16340151Application Date: 2017-10-18
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Publication No.: US10538490B2Publication Date: 2020-01-21
- Inventor: Matthias Eckhardt , Stefan Peters , Holger Wagner
- Applicant: Boehringer Ingelheim International GmbH
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent David L. Kershner
- Priority: EP16195431 20161025
- International Application: PCT/EP2017/076618 WO 20171018
- International Announcement: WO2018/077699 WO 20180503
- Main IPC: C07D213/74
- IPC: C07D213/74 ; A61P3/00 ; A61K31/44 ; C07D401/12 ; C07D405/12 ; C07D417/12 ; C07D409/12

Abstract:
The present invention relates to compounds of general formula I, wherein the groups R, R1, R2, R3, m and n are defined herein, which have valuable pharmacological properties, including binding to the GPR40 receptor and modulating its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2. Furthermore, the invention relates to novel intermediates, useful for the synthesis of compounds of formula I.
Public/Granted literature
- US20190241521A1 Benzylaminopyridylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof Public/Granted day:2019-08-08
Information query
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