Invention Grant
![1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 inhibitors](/docs/US/2020-01-21/US10538525B2/abs.jpg.600x600.jpg)
- Patent Title: 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 inhibitors
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Application No.: US16051612Application Date: 2018-08-01
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Publication No.: US10538525B2Publication Date: 2020-01-21
- Inventor: Karsten Juhl , Mikkel Jessing , Morten Langgård , Paulo Jorge Vieira Vital , Mauro Marigo , Jan Kehler , Lars Kyhn Rasmussen
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: DK201600221 20160412
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04 ; A61K31/437 ; A61K31/519
![1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 inhibitors](/abs-image/US/2020/01/21/US10538525B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.
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