Invention Grant
- Patent Title: Opsin polypeptides and methods of use thereof
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Application No.: US16115303Application Date: 2018-08-28
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Publication No.: US10538560B2Publication Date: 2020-01-21
- Inventor: Karl Deisseroth , Feng Zhang , Viviana Gradinaru
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Rudy J. Ng; Paula A. Borden
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C12N13/00 ; A61N5/06 ; C07K14/415 ; A61K48/00 ; A61K38/00 ; C07K14/405 ; C07K14/195
Abstract:
The present disclosure provides opsins, including variant opsins with increased activity and/or increased trafficking to the plasma membrane. The opsins are useful in therapeutic and screening applications, which are also provided.
Public/Granted literature
- US20190071476A1 OPSIN POLYPEPTIDES AND METHODS OF USE THEREOF Public/Granted day:2019-03-07
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