Invention Grant
- Patent Title: Polypeptides and variants having improved activity, materials and processes relating thereto
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Application No.: US15460414Application Date: 2017-03-16
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Publication No.: US10538746B2Publication Date: 2020-01-21
- Inventor: Alexander Brett Foster , Adriana Leonora Botes
- Applicant: INVISTA North American S.á r.l.
- Applicant Address: US DE Wilmington
- Assignee: INVISTA North America S.à r.l.
- Current Assignee: INVISTA North America S.à r.l.
- Current Assignee Address: US DE Wilmington
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Main IPC: C12N9/02
- IPC: C12N9/02 ; C07C59/147 ; C12P7/40

Abstract:
The disclosure relates to polypeptides having carboxylic acid reductase (CAR) activity, including enzymes that catalyse the irreversible reduction of carboxylic acids, such as pimelic acid and adipic acid, to their respective semialdehydes. The enzymes have been engineered to have higher activity over a corresponding wild type enzyme. Provided herein are novel polypeptides and uses thereof related to the same.
Public/Granted literature
- US20170298325A1 POLYPEPTIDES AND VARIANTS HAVING IMPROVED ACTIVITY, MATERIALS AND PROCESSES RELATING THERETO Public/Granted day:2017-10-19
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