Invention Grant
- Patent Title: Methods for categorizing and treating subjects at risk for pulmonary exacerbation and disease progression
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Application No.: US16134757Application Date: 2018-09-18
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Publication No.: US10539558B2Publication Date: 2020-01-21
- Inventor: Milene Saavedra
- Applicant: National Jewish Health
- Applicant Address: US CO Denver
- Assignee: National Jewish Health
- Current Assignee: National Jewish Health
- Current Assignee Address: US CO Denver
- Agency: Sheridan Ross P.C.
- Main IPC: C12P19/34
- IPC: C12P19/34 ; G01N33/537 ; C12Q1/6883 ; G01N33/68 ; G16H50/30 ; G16B40/00 ; G16C99/00 ; G06F19/00
Abstract:
The present invention is related to novel methods for for determining pulmonary disease progression severity in a subject having cystic fibrosis by detecting mRNA expression levels of CD64 in a whole blood sample for the subject and calculating a disease risk score, wherein the disease risk score correlates to the risk score for mild, moderate or severe pulmonary disease progression at exacerbation and treating the subject accordingly.
Public/Granted literature
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