Invention Grant
- Patent Title: Macrocycle and composition comprising thereof
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Application No.: US16081611Application Date: 2017-02-23
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Publication No.: US10543199B2Publication Date: 2020-01-28
- Inventor: Yihan Wang , Huanyin Li
- Applicant: Shenzhen TargetRx, Inc.
- Applicant Address: CN Shenzhen, Guangdong
- Assignee: Shenzhen TargetRx, Inc.
- Current Assignee: Shenzhen TargetRx, Inc.
- Current Assignee Address: CN Shenzhen, Guangdong
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: CN201610117814 20160303
- International Application: PCT/CN2017/074555 WO 20170223
- International Announcement: WO2017/148325 WO 20170908
- Main IPC: A61K45/06
- IPC: A61K45/06 ; A61K31/439 ; A61K35/00 ; A61P35/00

Abstract:
A macrocycle represented by formula (I) and a pharmaceutical composition comprising the macrocycle, or a crystalline form, pharmaceutically acceptable salt, hydrate or solvent compound, stereoisomer, prodrug, or isotopic variant of the macrocycle. The macrocycle and the composition thereof inhibit a protein kinase.
Public/Granted literature
- US20190060292A1 MACROCYCLE AND COMPOSITION COMPRISING THEREOF Public/Granted day:2019-02-28
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