Invention Grant
- Patent Title: Substituted amines for treating cardiac diseases
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Application No.: US15933889Application Date: 2018-03-23
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Publication No.: US10543212B2Publication Date: 2020-01-28
- Inventor: Nobuyuki Matsunaga , Takashi Nakahata , Yuta Tanaka , Hiroki Takahagi , Yasufumi Miyamoto , Rei Okamoto , Takeshi Yoshikawa , Yoshito Terao , Takafumi Yukawa , Keiko Kakegawa , Yoichi Nishikawa , Terufumi Takagi , Masashi Takahashi , Mallareddy Komandla , Lily Kwok , Joanne Miura , Mark Sabat , Nicholas Scorah , Paul Tanis , John Tyhonas , Phong H. Vu , Haixia Wang , Xiaolun Wang , Junya Shirai , Tomohiro Okawa , Zenyu Shiokawa , Akito Shibuya
- Applicant: Cardurion Pharmaceuticals, LLC
- Applicant Address: US MA Cambridge
- Assignee: Cardurion Pharmaceuticals, LLC
- Current Assignee: Cardurion Pharmaceuticals, LLC
- Current Assignee Address: US MA Cambridge
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: C07C211/39
- IPC: C07C211/39 ; A61K31/506 ; A61P9/06 ; A61K31/5377
Abstract:
The present invention provides a compound having a CaMKII inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of cardiac diseases (particularly catecholaminergic polymorphic ventricular tachycardia, postoperative atrial fibrillation, heart failure, fatal arrhythmia) and the like.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
Public/Granted literature
- US20180280389A1 HETEROCYCLIC COMPOUND Public/Granted day:2018-10-04
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