Invention Grant
- Patent Title: Compositions and methods for treating cancer with anti-CD22 immunotherapy
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Application No.: US16161542Application Date: 2018-10-16
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Publication No.: US10543263B2Publication Date: 2020-01-28
- Inventor: Rimas J. Orentas , Dina Schneider , Boro Dropulic , Dimiter S. Dimitrov , Zhongyu Zhu
- Applicant: LentigenTechnology, Inc. , The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Gaithersburg US MD Bethesda
- Assignee: Lentigen Technology Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee: Lentigen Technology Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Gaithersburg US MD Bethesda
- Agency: Fish & Richardson P.C.
- Agent Serge Sira, Esq.
- Main IPC: C12N15/63
- IPC: C12N15/63 ; C12N15/13 ; C07K14/47 ; A61K39/395 ; A61K39/00 ; C07K16/28 ; C07K14/705 ; C07K14/725 ; A61P35/00

Abstract:
Chimeric antigen receptors (CARs) containing CD22 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the CARs are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making CAR T cells are also disclosed.
Public/Granted literature
- US20190099476A1 Compositions and Methods For Treating Cancer With Anti-CD22 Immunotherapy Public/Granted day:2019-04-04
Information query
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