Invention Grant
- Patent Title: Cancer prevention and therapy by inhibiting soluble tumor necrosis factor
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Application No.: US15776061Application Date: 2016-12-14
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Publication No.: US10543264B2Publication Date: 2020-01-28
- Inventor: Nikola L. Vujanovic , Lazar Vujanovic
- Applicant: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Applicant Address: US PA Pittsburgh
- Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
- Current Assignee Address: US PA Pittsburgh
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US2016/066552 WO 20161214
- International Announcement: WO2017/106278 WO 20170622
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53 ; A61K39/00 ; A61K38/20 ; C07K14/525 ; A61P35/00 ; A61K45/06
Abstract:
Methods are disclosed for inhibiting the development of a tumor in a subject. The methods include administering to a subject a therapeutically effective amount of a dominant negative tumor necrosis factor (DN-TNF)-α protein and/or a nucleic acid encoding the DN-TNF-α protein. The DN-TNF-α protein and/or a nucleic acid encoding the DN-TNF-α protein can be administered alone or in combination with other agents.
Public/Granted literature
- US20190336591A1 CANCER PREVENTION AND THERAPY BY INHIBITING SOLUBLE TUMOR NECROSIS FACTOR Public/Granted day:2019-11-07
Information query
