A video cache rule generation system for generating cache rules for caching and playing back a video includes an obtaining module, a determining module, an extracting module, a comparing module, and a generating module. The obtaining module obtains URL addresses. The determining module determines whether each URL address belongs to a video URL address according to a media tag library. The extracting module divides a first URL address into chunks and extracts first key chunks from the chunks after division. The comparing module compares each first key chunk with a key chunk subclass, and marks a second key chunk where the second key chunk is found to be different from the key chunk subclass. The generating module generates a cache rule through generating a list of marked key parameter chunks. A video cache rule generation method is also provided.