Disclosed are various embodiments for providing interactive electronic commerce functionality via graphical overlays on live streaming video. An indication is received that an item is featured or discussed in a live video stream. The live video stream is sent to a client. Data encoding a selectable graphical overlay is sent to the client in response to the indication. The selectable graphical overlay is configured to be rendered by the client relative to the live video stream. A selection of the selectable graphical overlay is configured to perform an interactive function relative to the item.