A duodenoscope protected with disposable consumables comprises a body having an insertion portion covered with a cuff, and a disposable forceps passage tube inserted into a tube of the body. A distal end portion of the body is covered with an end cap, which is integrally connected to the cuff and to the disposable forceps passage tube. The end cap is made of transparent elastic material with an elongated opening, compatible in shape to an opening of the distal end portion of the duodenoscope body, and further comprises a soft connection port in a shape of a pipe with a small-orifice end secured onto the disposable forceps passage tube, and a large orifice end secured onto an edge of the elongated opening. A forceps-lifting unit is disposed at the distal end portion of the duodenoscope body, and comprises a grooved pulley coupled with a steel wire for maneuverability.