An automated medical diagnostic system includes antennas, transmitter, receiver, and a processor-based device or system. Excitations signals are transmitted into bodily tissue at each of a plurality of discrete frequencies (e.g., steps of 1 MHz from 300 MHz to 2500 MHz) or unequal steps. The response signals are received and analyzed against the excitation signals at each of a number of the frequencies, for example determining gain/loss due to passage through bodily tissue. The results are analyzed for patterns indicative of a presence or absence of an abnormal condition, and results presented.