Invention Grant
- Patent Title: Pharmaceutical composition for oral administration
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Application No.: US15569682Application Date: 2016-04-27
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Publication No.: US10548845B2Publication Date: 2020-02-04
- Inventor: Yumiko Suda , Toshiro Sakai , Ryo Kojima , Dal Oyama , Koji Nishimura , Kumi Naiki
- Applicant: ASTELLAS PHARMA INC.
- Applicant Address: JP Tokyo
- Assignee: ASTELLAS PHARMA INC.
- Current Assignee: ASTELLAS PHARMA INC.
- Current Assignee Address: JP Tokyo
- Agency: Kilpatrick Townsend & Stockton LLP
- Priority: JP2015-092005 20150428
- International Application: PCT/JP2016/063151 WO 20160427
- International Announcement: WO2016/175230 WO 20161103
- Main IPC: A61K9/20
- IPC: A61K9/20 ; A61K31/497 ; A61K47/02 ; A61K47/38 ; A61P13/02 ; A61P13/10

Abstract:
Disclosed is a pharmaceutical composition for oral administration, comprising 1-{5-[(5-{[(2R)-2-ethylpyrrolidin-1-yl]methyl}-4-[4-methoxy-3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl)carbamoyl]pyrazin-2-yl}pyperidine-4-carboxylic acid, which is a compound having pH-dependent solubility, or a pharmaceutically acceptable salt thereof, and a cellulose derivative. In the pharmaceutical composition for oral administration, the solubility and absorbability of the drug are improved.
Public/Granted literature
- US10583087B2 Pharmaceutical composition for oral administration Public/Granted day:2020-03-10
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