Invention Grant
- Patent Title: Muscarinic agonists
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Application No.: US15749743Application Date: 2016-08-03
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Publication No.: US10548884B2Publication Date: 2020-02-04
- Inventor: Giles Albert Brown , Miles Stuart Congreve , Mark Pickworth , Mark David Rackham , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Cambridge
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: GB1513740.9 20150803
- International Application: PCT/GB2016/052384 WO 20160803
- International Announcement: WO2017/021728 WO 20170209
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D413/14 ; A61P25/14 ; A61P25/28 ; A61K31/4523 ; A61K31/451

Abstract:
This invention relates to compounds that are agonists of the muscarinic M4 receptor and/or M4 receptor and which are useful in the treatment of muscarinic M1/M4 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds include those according to formula 1a or a salt thereof, wherein n, p, Q, R1, R2, R3, R9 and R4 are as defined herein.
Public/Granted literature
- US20180228791A1 MUSCARINIC AGONISTS Public/Granted day:2018-08-16
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